International Journal of Applied Chemical and Biological Sciences

ISSN: 2582-788X (Online)

International Journal of Applied Chemical and Biological Sciences
Home Archive Volume 3 - Issue 2 Screening of phytochemicals from Couroupita guianensis as drug candidates against lethal diseases using insilico analysis

Volume 3   Issue 2

Research Article

Screening of phytochemicals from Couroupita guianensis as drug candidates against lethal diseases using insilico analysis

Article Identifier: https://identifier.visnav.in/1.0001/ijacbs-22a-30001/
India
Abstract

Couroupita guianensis is a deciduous, huge, versatile tree flourishing with brown, green, pink, white colours and also with phytochemicals like alkaloids, flavonoids, Terpenoids, Saponins, tannins, carbohydrates that are ready to serve to the plant as well as humans. This huge plant also is seen to have some pharmacological activities like antimicrobial, antifungal, antioxidant, anti-diabetic, anti-inflammatory and anticancer. With the passing time, there is a greater demand for effective natural medication. Physicochemical characteristics, drug similarity, toxicity, and efficacy of phytochemicals against numerous targets may now be evaluated using online tools, thanks to a wide database and technical advancements. The insilico method is efficient since it saves time and money. Clinical trials could benefit from such a strategy to increase medication development and market acceptance. Natural sources can provide a pool of molecules for any disease target when they are evaluated for potential therapeutic candidates. Some of the software utilized in the study to evaluate phytochemicals from a plant source included SwissADME and SwissDock. Due to their superior ADME qualities, reduced toxicity, and docking, four of the six phytochemicals studied from these plants are potential therapeutic candidates against diverse targets.

Keywords: Couroupita guianensis, Cancer, Diabetes, insilico ADMET, Docking
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