ISSN: 2582-788X (Online)
ANTI-INFLAMMATORY METABOLITES FROM MARINE ORGANISMS
Inflammation is a complex reaction by the body against any self-created infection or foreign particle invasion causing body cell and tissue injury. The inflammation can heal these injuries but sometimes it can turn aggressive causing severe chronic pain such as different arthritis, retinitis and much multiple sclerosis. To combat the effect of inflammation synthetic anti-inflammatory agents (steroids and NSAIDS) are widely used. Many NSAIDS drugs like diclofenac, asprin, indomethacin etc. are effective with lesser side effect. These drugs are effective but it does not eradicate the disease from the body and its regular consumption may lead to renal ulcers, gastrointestinal diseases etc. Thus in recent years the researchers are more focused in finding the metabolites to produce natural drugs for combating inflammation. The different metabolites from plants are mostly and widely exploited for natural inflammation drugs which are much effective and safe. It is also observed that many commonly found marine organisms produce some effective metabolites. These metabolites from marine sources are comparatively as effective as the synthetic anti-inflammatory agents. This review showcases the possible effective metabolites from marine organism in inhibiting the inflammation and how this discovery can bring sustainable global change.