International Journal of Applied Chemical and Biological Sciences

ISSN: 2582-788X (Online)

International Journal of Applied Chemical and Biological Sciences
Home Archive Volume 1 - Issue 3 Anti – hyperglycemic activity of Aloe vera ethanolic extract against mouse 3T3-L1 adipocyte cell line

Volume 1   Issue 3

Review Article

Anti – hyperglycemic activity of Aloe vera ethanolic extract against mouse 3T3-L1 adipocyte cell line

Article Identifier: https://identifier.visnav.in/1.0001/ijacbs-20i-01302/
Abstract

Several traditional medicinal plants have been investigated concerning their anti-obesity potential one such sources is Aloe vera. The medication is reported for different helpful properties like, love potion and counteractant, healing arsenic harming, tonic, restoring, diuretic, purgative, uterotonic, sterility in ladies, etc. These are medicationally very helpful especially in curing diabetes. The plants are explored for many different biopotential activities like antiulcerogenic, hypolipidemic, nephroprotective, mitigating, antidermatophytic, cancer prevention agent, antimicrobial and insecticidal exercises. In this study we performed phytochemical screening of various Aloe vera extracts to compare its bioactive potential. The control group of 700µg was compared with ethanolic extract of Aloe vera and observed that it reduced the expression of TNF α (Tumor necrosis factor) and Interleukin 6 (IL-6). It even increased the expression of adiponectin which revealed the presences of different phytochemicals are present in ethanol extract. The data created by this specific investigation gives pertinent pharmacognostic and phytochemical information required for appropriate distinguishing proof and verification of this specific species. The present study emphasis in finding the anti-hypergycemic activity of Aloe vera on cell lines and highlights the phytochemical and pharmacological aspects of A. vera.

Keywords: 3T3L1 Cell line, aloe vera, adipogenesis, antiulcerogenic, phytochemical
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